Ten years ago, I finished my doctorate in Health Administration and wrote Health Attitude: Unraveling and Solving the Complexities of Healthcare. One of the topics I wrote numerous magazine articles about and on-the-air interviews was about direct-to-consumer (DTC) TV advertising. I felt strongly about the issue and ten years later I feel even more strongly about it. DTC TV advertising is not needed and has negative effects as I will describe below.
At the time, Millions of viewers of the Superbowl watched a celebrity step out of a limo and heard Mario Lopez, Jr., television host and actor, highlight the need to fight her toenail fungus. The ad suggested people with toenail fungus need Jublia, a $1,000 drug not covered by Medicare. A clinical study showed the cure rate for the drug was 15%. Anyone with toenail fungus has either talked to their doctor about it, researched it online, or is not bothered by any symptoms. The ad had more than 2,000 TV airings. The AMA, which represents more than 200,000 physicians in every state, said the growing proliferation of TV ads is driving demand for expensive drugs despite the availability of clinically effective and less costly alternatives. Following are my six reasons why the ban should be implemented ASAP.
The pharmaceutical industry has done a lot of good for the world. Most babies born in 1900 did not live past age 50. Although the United States ranks #49 in the world, our life expectancy has risen to 79. Several factors have led to the increasing life span. Drugs created by the pharmaceutical industry have certainly contributed. The industry has also created drugs which enable people crippled with arthritis and other diseases to be happy and productive. Pharmaceutical research to create the wonder drugs is expensive and risky. Many drugs do not make it to the market. Profit creates the incentive to take the risks and the return on investment for the drug industry deserves to be above average. However, it has become disproportional. Pharmaceutical companies have a median gross profit margin of 76.5%. The S&P 500 companies have a median gross profit margin of 37.4%. Congress has given the industry a blank check to set prices. There are numerous watchdogs who look at industry merger and acquisition activity, anticompetitive behavior, and a ban of direct-to-consumer TV advertising.
Now the question is whether the new administration can make an impact on the cost of healthcare. The pharmaceutical industry maintains a significant lobbying presence and provides substantial political contributions. As of 2024, the pharmaceutical and health products industry employs 1,478 lobbyists, with 58% of them being former government employees. This high percentage of “revolving door” lobbyists indicates the industry’s strong connections to government.
In 2024, the pharmaceutical and health products industry spent $293,701,614 on lobbying. This represents a significant increase from previous years. For the 2023-2024 election cycle, pharmaceutical and health products Political Action Committees (PACs) have contributed $7,638,410 to political candidates, $3,269,050 to Democrats and $4,315,360 to Republicans.
Around the time I published Health Attitude, the lobby convinced Congress to ban Medicare from negotiating the price of drugs. (They even convinced Congress to give hundreds of millions of dollars in preferential treatment to individual drug companies). The last administration took victory laps after more than ten years. They said they had taken down big pharma for the benefit of consumers on Medicare. Medicare covers more than 4,000 drugs. The new ability to negotiate the price of drugs for Medicare was announced in 2022. Look at the details. The negotiated prices would start in 2026 for only 10 drugs. For 2027 the list would grow to 15 drugs. Can you imagine GM or Tesla exempting from negotiations for 99.8% of the millions of parts it buys? The government has. Meanwhile many taxpayers struggle to pay the rapidly growing cost of drugs. Some skip doses or share with family members. Some go bankrupt. Pharmaceutical industry, 1. Taxpayers, 0.
There are many lobbies; every industry has them. At times they do good things and prevent Congress from doing something stupid. In the case of pharmaceuticals, it is clear the lobby has a lock on Congress and causes them to act more for the benefit of the drug industry than for consumers.
In this section, I share what I am up to, pictures of the week, what is new in AI and crypto, and more.
I finished the MIT course on January 18. They say it takes 14 days to grade the course and then some more time to the end and issuance of certificates. The course was AI in Healthcare. I suggest they develop some AI in e-learning.
This week has seen significant developments in the AI landscape, particularly with the emergence of DeepSeek, a Chinese AI company that has taken the tech world by storm.
DeepSeek’s Breakthrough
DeepSeek, a relatively unknown Chinese technology company, has made headlines with the release of its DeepSeek-R1 model. This open-source AI model has reportedly matched the performance of OpenAI’s GPT o1 across various core tasks, but at a fraction of the cost[1][3]. The company claims to have developed the R1 model for less than $6 million, which is significantly less than the investments made by major U.S. tech companies in AI development[4].
Key Features of DeepSeek-R1:
– Focuses on advanced reasoning tasks
– Has 671 billion parameters with a context length of 128,000
– Uses a mixture-of-experts architecture
– Capable of handling a range of tasks[4]
Market Impact
The release of DeepSeek-R1 has had a significant impact on the stock market. On January 27, 2025, the Nasdaq Composite dropped by 3.4% at market opening, with Nvidia experiencing a 17% decline, losing approximately $600 billion in market capitalization[4]. This sell-off was triggered by investors reassessing AI valuations in light of DeepSeek’s low-cost innovation[4].
Other AI Developments
1. DeepSeek also released Janus-Pro-7B, a vision model capable of understanding and generating images[4].
2. Alibaba released Qwen2.5-Max, which the company claims outperforms DeepSeek’s V3 model[5].
3. Moonshot AI and ByteDance released new reasoning models, Kimi 1.5 and 1.5-pro, which they claim can outperform OpenAI’s o1 on some benchmark tests[5].
4. OpenAI previewed its first general-purpose AI agent called Operator, though it has been overshadowed by the focus on DeepSeek[9].
Implications and Reactions
The success of DeepSeek has raised concerns in the U.S. about technological dominance in AI. Some have compared it to the “Sputnik moment” of the AI era, referencing the Soviet Union’s space race breakthrough in the 1950s[4].
Sam Altman, CEO of OpenAI, responded to the news on Twitter, acknowledging DeepSeek’s achievement while expressing confidence in OpenAI’s future developments[9].
Nvidia released a statement describing DeepSeek as “an excellent AI advancement” and emphasized that it demonstrates the effectiveness of Test Time Scaling techniques[9].
This week’s developments highlight the rapidly evolving nature of AI technology and the increasing global competition in this field.
This week has seen several significant developments in the cryptocurrency market, with notable events and trends shaping the landscape:
Bitcoin’s New All-Time High
Bitcoin reached a new all-time high of over $109,000 on January 20, 2025, coinciding with the inauguration of U.S. President Donald Trump[5]. This surge represents a remarkable 162% price increase over the past year, indicating growing mainstream interest in cryptocurrencies[5].
Trump’s Executive Order on Digital Assets
President Trump signed an executive order on digital assets, setting up a working group to examine current crypto regulations and make recommendations for the path forward[4]. This order also includes the potential establishment of a bitcoin strategic reserve, fulfilling key promises made during his campaign[4].
SEC’s Crypto-Friendly Stance
The Securities and Exchange Commission (SEC) has become more friendly to the crypto industry by rescinding SAB 121, creating a Crypto Task Force, and announcing pro-crypto Mark Uyeda as acting chairman[4]. This shift in regulatory approach has led to a flood of applications for new types of crypto ETFs[4].
Mantra’s Record High
Mantra (OM), a leading project in the real-world asset (RWA) tokenization industry, reached a record high of $5.08[3]. This surge was partly due to BlackRock’s CEO calling for regulators to approve the tokenization of stocks and bonds[3].
Optimism and Sui Token Unlocks
Optimism (OP) is preparing to unlock tokens worth over $53 million, representing 1.48% of the float[3]. Similarly, Sui (SUI) is set to unlock $138 million in tokens this week[3]. These events could potentially impact the tokens’ prices and market dynamics.
Emerging Projects
Pengu Unleashed ($PUNGU) has gained attention by raising $2.5 million in its first week of presale and pledging $1 million to penguin habitat conservation[8]. Built on Layer 2 rollup technology, it offers fast, secure, and low-cost transactions with staking rewards of up to 300% APY[8].
Market Turbulence
Despite the overall bullish sentiment, the crypto market experienced some turbulence early this week. Bitcoin fell to $100,439, marking a decline of over 6.7% over the past week, while Ether dropped to $3,086, reflecting a decrease of more than 7.5% in a week[6].
These developments highlight the dynamic nature of the cryptocurrency market, with regulatory changes, technological advancements, and market sentiment all playing crucial roles in shaping the industry’s trajectory.
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